Drug Uses
Aldactone is in a class of drugs called potassium-sparing diuretics (water pill). It is used to reduce the amount of fluid in your body without causing the loss of potassium.
Aldactone is used to treat edema (swelling) and hypertension (high blood pressure).
Aldactone is also used to treat potassium deficiency and hyperaldosteronism (a hormonal disorder).
How Taken
Aldactone comes as a tablet to take by mouth. It usually is taken once a day in the morning with breakfast or twice a day with breakfast and lunch. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Aldactone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Aldactone controls high blood pressure but does not cure it. Continue to take Aldactone even if you feel well. Do not stop taking Aldactone without talking to your doctor.
Warnings/Precautions
Before taking Aldactone, tell your doctor if you have kidney disease; have liver disease; have diabetes mellitus; have high levels of potassium in your blood; or are taking a potassium supplement or an angiotensin-converting-enzyme inhibitor (ACE inhibitor).
You may not be able to take Aldactone, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Aldactone is in the FDA pregnancy category D. This means that Aldactone is known to harm an unborn baby. Do not take Aldactone if you are pregnant.
It is not known whether Aldactone passes into breast milk. Do not take Aldactone without first talking to your doctor if you are breast-feeding a baby.
Missed Dose
Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Possible Side Effects
Stop taking Aldactone and seek emergency medical attention if you experience any of the following serious side effects: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); an irregular heartbeat, shortness of breath, fatigue, confusion, weakness, numbness, or tingling (caused by high levels of potassium in your blood); or decreased urination.
Other, less serious side effects may be more likely to occur. Continue to take Aldactone and talk to your doctor if you experience unusual headache or dizziness; nausea, diarrhea, or a decrease in appetite; dry mouth; bloating; muscle cramps; or lowering of the voice, excessive hair growth, or enlarged breasts.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Storage
Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medicine that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medicine.
Overdose
Acute over dosage of Aldactone may be manifested by drowsiness, mental confusion, nausea, vomiting, dizziness, or diarrhea. Seek emergency medical attention.
More Information
Aldactone is also used in combination with other medicines to treat precocious puberty or myasthenia gravis. Aldactone also may be used to treat certain female patients with abnormal facial hair. Talk to your doctor about the possible risks of using this medicine for your condition.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Previous studies had already suggested that a link between low levels of vitamin D in the blood and hypertension existed. Definitive data in the form of prospective studies, however, had been somewhat limited. The said study followed some 1,484 women from the Nurses' Health Study II. The study subjects did not have hypertension at its commencement, and the women were aged from 32 to 52 years, with their average age being about 43 years.
After having accounted for a series of factors which could affect blood pressure, including age, race, body mass index, level of physical activity, family history of the disease, use of oral contraceptives, as well as blood levels of calcium and phosphorous, the study team found that women with lower levels of vitamin D had much higher incidence of hypertension.
Women who ranked in the lowest quartile for blood levels of 25-hydroxyvitamin D, or 25(OH)D, had a 66% higher risk of having high blood pressure, as compared to those in the highest quartile. The median 25(OH)D blood levels were also lower in hypertension sufferers (25.6 ng/mL) as compared with those who did not have the condition (27.3 ng/mL).
All in all, almost two thirds, or 65.7% of the women, were found to be deficient in vitamin D (less than 30.0 ng /mL). That, in itself, is quite a startling statistic. Perhaps nurses spend the majority of their days indoors, away from the health-promoting rays of the sun. And it was found that those deficient in the vitamin were 47% likelier to develop high blood pressure than those who had enough of it.
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