Drug Uses

Buspar is used to treat generalized anxiety disorder. Your doctor may use this medicine to treat other conditions as well. Buspar affects the chemicals in your brain that may have become unbalanced and are causing anxiety.

How Taken

Take Buspar with food or milk if stomach upset occurs. It is important to take this medication exactly as prescribed. Do not increase your dose or take more often than prescribed. Symptoms will begin to improve within 7 to 10 days of starting this medication. However, it may take 3 to 4 weeks for the full benefit of the medication to be apparent.

Warnings/Precautions

Before taking Buspar, tell your doctor your medical history especially: kidney or liver disease, any drug allergies. Limit alcohol intake as it may intensify the dizziness and/or drowsiness effects of Buspar. Use caution when engaging in activities requiring alertness such as driving. Tell your doctor if you are pregnant before using this drug. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

Missed Dose

Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.

Possible Side Effects

Buspar may cause drowsiness, dizziness, lightheadedness, fatigue, weakness, vivid dreams, sleeplessness, dry skin, blurred vision, altered sense of taste and smell, weight gain, muscle aches, ringing in the ears, nausea, and headaches. If these effects persist or worsen, notify your doctor. Notify your doctor if you experience: abnormal movements or "twitches" of the face or neck muscles, other involuntary movements or tremors, depression, confusion, incoordination, chest pain, breathing difficulties. If you notice other effects not listed above, contact your doctor or pharmacist.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, dizziness, drowsiness, and decreased pupil size.

More Information

Before taking Buspar tell your doctor of all over-the-counter or prescription drugs you may use especially: other drugs for anxiety or depression, azole or macrolide antibiotics, haloperidol, narcotic pain medications. Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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The term "comorbidity" refers to the presence of any two or more illnesses in the same person. These illnesses can be medical or psychiatric conditions, as well as drug use disorders, including alcoholism. Comorbid illnesses may occur simultaneously or sequentially. The fact that two illnesses are comorbid, however, does not necessarily imply that one is the cause of the other, even if one occurs first. An understanding of comorbidity is essential in developing effective treatment and prevention efforts. For example, since alcoholism causes liver disease, measures to decrease alcohol consumption will help reduce the incidence of liver disease. With respect to treatment, persons exhibiting comorbid alcohol-related and medical or psychiatric disorders often fall through the cracks of the health care system because of administrative distinctions among addiction, medical, and mental health-related services. Patients are often forced to choose between clinical settings, often resulting in neglect of one condition (1). Alcoholism and other disorders might be related in a number of ways, including the following (2,3): 1) Alcoholism and a second disorder can co-occur, either sequentially or simultaneously, by coincidence. 2) Alcoholism can cause various medical and psychiatric conditions or increase their severity. 3) Comorbid disorders might cause alcoholism or increase its severity. 4) Both alcoholism and the comorbid disorder may be caused, separately, by some third condition. 5) Alcohol use or alcohol withdrawal can produce symptoms that mimic those of an independent psychiatric disorder. Research on the nature of the relationship between comorbid disorders generally relies on surveys of either the clinical population (persons in treatment) or the general population. Most studies of comorbidity are based on clinical samples. This may result in inflated estimates of comorbidity, since persons with multiple ailments may be more likely to seek treatment (Berkson's fallacy) (4). This trend may be countered to some extent by the reluctance of some alcoholism treatment centers to admit persons exhibiting serious psychiatric problems. Thus, the prevalence of comorbid psychiatric disorders among alcoholics in treatment does not reflect the actual prevalence of such comorbidity in the community (3). Additional methodological difficulties complicate both clinical and general population investigations. For example, estimates of comorbidity will also vary depending on how alcohol use disorders are defined. Definitions of alcoholism have included 1) formal definitions of abuse and dependence appearing in psychi atric classification systems such as the DSM-III-R; 2) alcohol-related symptom ratings; 3) serious manifestations of physiological dependence (i.e., tolerance and withdrawal); and 4) various levels of heavy alcohol consumption. Since alcohol use, alcohol withdrawal, and alcohol abuse and dependence may each relate to comorbid conditions in an entirely different way, it is essential when evaluating comorbidity to clarify which aspects of alcohol use are involved (5). Similar considerations apply to the evaluation of comorbid disorders. For example, when evaluating depression, it is important to distinguish among sadness, grief, and major depressive disorder (2). An important source of comorbidity data is the Epidemiologic Catchment Area (ECA) program of the National Institute of Mental Health (6). The ECA surveyed more than 20,000 respondents residing in households, group homes, and long-term institutions in five sites across the United States (7) to provide data about the prevalence and incidence of psychiatric dis orders, as well as issues related to treatment. (Prevalence is the number of existing cases; incidence is the number of new cases.)

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