Drug Uses
Cleocin T is used to treat acne vulgaris.
How Taken
Apply a thin film of Cleocin T Topical Solution or use a Cleocin T Topical Solution pledget for the application of Cleocin T twice daily to affected area. You may use more than one pledget. Use each pledget only once and then discard it.
Warnings/Precautions
It is not known whether clindamycin is excreted in human milk following use of Cleocin T. However, orally and parenterally administered clindamycin has been reported to appear in breast milk.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Possible Side Effects
Orally and parenterally administered Cleocin T has been associated with severe colitis which may end fatally. Abdominal pain and gastrointestinal disturbances as well as gram-negative folliculitis have also been reported in association with the use of topical formulations of clindamycin.
Storage
Do not use pledget if the seal is broken. Discard after single use. Keep all liquid dosage forms in containers tightly closed out of the reach of children.
Overdose
Topically applied Cleocin T can be absorbed in sufficient amounts to produce systemic effects. Seek emergency medical attention if an overdose is suspected.
More Information
Use caution when taking Cleocin T together with neuromuscular blocking agents.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Two proteins may help fight skin cancer
CHAPEL HILL, N.C., March 19 (UPI) -- U.S. researchers have identified two proteins that might help the body protect itself against skin cancer.
The University of North Carolina at Chapel Hill School of Medicine study indicates the proteins, named Timeless and Tipin, form a complex that regulates the rate at which DNA is replicated after exposure to ultraviolet radiation.
Ultraviolet radiation can damage skin cells and, if left unrepaired by the cell, it can cause cancerous mutations.
But before cells begin to divide, they must replicate their DNA to form new daughter cells. If damage in the DNA is discovered even after the cell has started to replicate its DNA, the Timeless/Tipin complex sends a signal that slows the replication. That slowdown, said the researchers, might give the cell additional time to repair its DNA and potentially save itself from becoming cancerous or from dying in response to ultraviolet radiation.
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