Drug Uses
Synalar Cream is used to reduce itching, redness, and swelling associated with many skin conditions.
How Taken
Apply a small amount of medicine to the affected area. Gently rub the medicine in until it is evenly distributed. Wash your hands after applying this medicine, unless your hands are part of treated area. Do not bandage or wrap the affected area unless directed otherwise by your doctor.
Warnings/Precautions
If your condition shows no signs of improvement or becomes worse within a few days, check with your doctor. Avoid contact with the eyes. Do not use Synalar Cream longer than the time prescribed. Tell your doctor if you are breast-feeding before taking this medicine.
Missed Dose
If you miss a dose, apply it as soon as you remember. If it is near the time of the next application, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Possible Side Effects
Some of the side effects you may experience include: skin thinning and discoloration, itching, burning, redness, or swelling not present before using this medicine.
Storage
Store Synalar Cream at room temperature, away from heat and light. Keep out of the reach of children.
Overdose
Synalar Cream may be harmful if swallowed. Seek emergency medical attention if an overdose is suspected.
More Information
Do not use this medicine for purposes other than those for which it was prescribed. Do not share Synalar Cream with others.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Smokers' Skin Is More Wrinkled, Even In Areas Shielded From Sunlight
Science Daily — In classic movies, cigarette smoking was used as shorthand to convey sultriness and beauty. In the real world, the connection between smoking and one's appearance -- as many studies have shown -- has more to do with premature signs of aging and less to do with glamour and refinement.
A new study from the University of Michigan Health System adds another dimension to the link between cigarette smoking and skin damage. The study suggests that smoking may be associated with a higher degree of aging on areas of skin, such as that of the inside of the upper arm, that are not normally exposed to sunlight.
"We examined non-facial skin that was protected from the sun, and found that the total number of packs of cigarettes smoked per day and the total years a person has smoked were linked with the amount of skin damage a person experienced," says Yolanda R. Helfrich, M.D., lead author and assistant professor of dermatology at the U-M Medical School.
The researchers developed a photonumeric scale that can be easily reproduced by other medical institutions to measure the degree of aging on patients' skin. The nine-point scale used information from photographs of the inside-upper-arm skin of the 77 participants.
Two medical residents and a medical student were asked to look at the photographs and assign a grade in which zero represented no fine wrinkling and eight represented severe fine wrinkling. The same three people reviewed photos of the participants one year later, and the scores were used to determine the level of increase in the skin damage.
Researchers also collected data about the participants from interviews, such as their age, ethnicity, history of cigarette smoking, use of non-steroidal anti-inflammatory drugs, use of dietary or herbal supplements, sun exposure, sunscreen use, tanning bed use and, for women, how many children they had given birth to, hormone therapy use and oral contraceptive use.
Among the people in the study who were current or former smokers, they had smoked an average of about 24 years. In all, among participants who were 45 years or older, the degree of skin aging was found to be significantly higher in smokers than nonsmokers.
In the 45-65 age group, smokers had an average score on the photonumeric scale of more than two, while nonsmokers had an average score of less than one. In the 65 and older age group, smokers had an average score of about six, while nonsmokers had an average score of approximately four.
In addition to Helfrich, authors were Abena Ofori, M.D.; Ted A. Hamilton, M.S.; Jennifer Lambert, M.S.; Anya King, M.P.H.; John J. Voorhees, M.D.; and senior author Sewon Kang, M.D., all of the U-M Department of Dermatology; and Le Yu, M.D., now with Cedars Sinai Medical Center in Los Angeles.
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