Drug Uses

Use Tetracycline to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

How Taken

The usual daily dose is 1g to 2g. Your doctor may increase the dosage in case of severe infections. You should continue therapy for at least 24 to 48 hours after the symptoms and fever have subsided.

Warnings/Precautions

Talk to your physician before taking this medicine if you are hypersensitive to tetracyclines. Using Tetracycline in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit and increases the risk of the development of drug-resistant bacteria.

Missed Dose

If you skip doses or do not complete the full course of therapy, you may risk a decrease in the effectiveness of the immediate treatment. Also there is a chance that bacteria will develop resistance and will not be treatable by Tetracycline or other antibacterial drugs in the future.

Possible Side Effects

Side effects you may experience may include: anorexia, epigastric distress, nausea, vomiting, diarrhea, bulky loose stools, stomatitis, sore throat, glossitis, black hairy tongue, dysphagia, hoarseness, enterocolitis, and inflammatory lesions (with candidal overgrowth) in the anogenital region.

Storage

Store the tablets at room temperature; avoid excessive heat. Dispense in tight, light-resistant containers. Keep out of the reach of children.

Overdose

In case of overdosage, seek emergency medical attention.

More Information

If you are undergoing long-term therapy, periodic laboratory evaluation of organ system function, including renal, hepatic, and hematopoietic systems, should be performed.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Scientists have confirmed their suspicions that a strain of hospital bacteria Staphylococcus aureus acquired resistance to the powerful drug vancomycin from another species of bacteria also commonly found in hospitals.
The two bacteria were present in the wound of a patient in a Michigan hospital in June 2002.
The confirmation came when researchers sequenced DNA from S. aureus and concluded that the DNA, which carried genes for vancomycin resistance, had almost certainly come from the bacterium Enterococcus faecalis. Apparently the resistance genes had “jumped” from one microbe to another.
Scientists have known that in the laboratory the two species can exchange genes for resistance to vancomycin. But the new study marks the first time scientists have documented how the exchange occurred in real life.
Scientists at the Centers for Disease Control and Prevention in Atlanta, Georgia, led the research. The findings appear in Science.
“The really important observation is that this [exchange] happened in a clinical environment,” says Steven R. Gill of The Institute for Genomic Research (TIGR) in Rockville, Maryland, where the DNA was sequenced.
S. aureus is already resistant to most antibiotics, and scientists had long-anticipated that the bacterium would become resistant to vancomycin, leaving physicians without a last-resort treatment.
More than a year ago, doctors’ fears came true when they discovered S. aureus resistant to vancomycin in a Michigan dialysis patient. Staph bacteria can still be treated with some antibiotics.
Bacterial genomes have large amounts of DNA that can move around on chromosomes, between organisms, and even jump between species. This enables them to pass traits such as drug resistance from one to another.
Antibiotic resistance is a growing health concern, which led the U.S. Department of Health and Human Services to launch a campaign in September called “Get Smart: Know When Antibiotics Work” to alert doctors and patients to be cautious in using antibiotics.

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